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    IMR

    IAPMD NEWS • ACHIEVEMENT

    Congratulations! IMR's Success at the IAPMD 11th Annual Scientific Meeting 2026

    August 2026 • Kuala Terengganu, Malaysia
    The Institute for Medical Research (IMR) extends its heartiest congratulations to Dr. Ainur Yusniza Yusof from the Autoimmune Unit, Allergy & Immunology Research Centre (AIRC) for winning the Bronze Award for Best Poster Presentation at the IAPMD 11th Annual Scientific Meeting 2026.
    Dr Ainur Yusniza Yusof receiving the IAPMD 2026 poster award IMR researchers at the IAPMD 11th Annual Scientific Meeting 2026 IAPMD 11th Annual Scientific Meeting 2026 award presentation
    Best Poster Presentation • Bronze Award
    Serological Characterization and Clinical Significance of Onconeuronal Autoantibodies in Suspected Paraneoplastic Syndrome
    Awardee: Dr. Ainur Yusniza Yusof
    Unit/Centre: Autoimmune Unit, Allergy & Immunology Research Centre (AIRC), IMR
    Category: Original Article
    Award: Best Poster Presentation Award – Bronze Award

    The scientific meeting took place on 3–4 August 2026 at the Raia Hotel & Convention Centre, Kuala Terengganu, Terengganu.

    The award recognises the scientific contribution of Dr. Ainur Yusniza Yusof and her research team in investigating the serological characteristics and clinical significance of onconeuronal autoantibodies in patients with suspected paraneoplastic syndrome.

    This achievement highlights the valuable contribution of medical research and pathology-related scientific work in advancing diagnostic understanding and improving patient care.

    “Excellence in medical research is the catalyst for elevating the quality of national healthcare.”
    Kudos and warmest congratulations to Dr. Ainur Yusniza Yusof!

    May this achievement continue to inspire researchers across the Institute for Medical Research and the Ministry of Health Malaysia to excel on scientific platforms locally and internationally.
    Source: Institute for Medical Research (IMR)
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    Case 9 : Mesonephric hyperplasia

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    A 46-year-old lady was diagnosed with adenocarcinoma in situ on pap smear and she underwent cervical cone biopsy. One representative section.

    ​Educational notes: 1. Section from the cervical cone biopsy shows mesonephric hyperplasia characterized by lobules of glands in the deeper part of the cervical wall. These glands are composed of a single layer of cuboidal epithelium without cytological atypia. The covering squamous epithelium and endocervical glands are devoid of dysplasia. 2. Presence of lobules of glands in the deeper part of the cervical wall stimulates infiltrative adenocarcinoma. However, entities such as mesonephric remnants and mesonephric hyperplasia need to be considered. Mesonephric remnants typically involve the deep layer of anterolateral wall of cervix along the path of the mesonephric duct. They may appear infiltrative and extend close to the luminal surface and intermingle with endocervical glands. In contrast, mesonephric hyperplasia has larger and more irregularly distributed glands as compared to mesonephric remnants. In the lobular type, the glands have exaggerated, clustered, lobular arrangement separated by variable amount of stroma. In the diffuse type, mesonephric hyperplasia displays predominantly non-clustered, extensive, and more diffuse proliferation. The least common duct type is characterized by hyperplastic epithelium with papillary tufting, and it may show clefted contours lacking intraluminal secretions. 
    3. Mesonephric glands are characteristically lined by a layer of simple flat or low cuboidal, non-ciliated cells with distinct basement membranes. They contain PAS-positive, diastase resistant material. Differing from adenocarcinoma or adenocarcinoma in situ, mesonephric glands lack nuclear atypia. Adenocarcinoma in situ is consistently characterized by nuclear enlargement, coarse chromatin, small single or multiple nucleoli, increased mitotic activity and variable nuclear stratification. An invasive adenocarcinoma shows complex architecture forming labyrinth or maze-like arrangement, and cribriform pattern with single gland profile. Although presence of stromal desmoplasia favors malignancy, distinction from a range of benign conditions showing stromal fibrosis, oedema and dense inflammation is critical.

    ​Reference 1. Zaino, R. Glandular Lesions of the Uterine Cervix. Mod Pathol 13, 261–274 (2000).